Re: “Although the implications of this finding must be better understood, these results do not alter the risk-benefit ratio favoring vaccination against COVID-19 to prevent severe clinical outcomes.”
Who is actually at risk of “severe clinical outcomes” with COVID-19?
I can't get too excited about finessed explanations of the molecular mechanism of spike's cardiotoxicity. The shots and their presumptuous mRNA platform are the problem and should be banned as any sort of 'public health' tool. Whether the siited study might lead to a treatment for the 'vaccine' injured might be another story.
How can worsening of clinical outcome after vaccination ever be considered good? There was increased spike uptake leading to myocarditis. Anotherwords antibodies did not neutralize it. Spike ended up in the cell undisturbed. Isnt that what happens in ADE, spike enters the cell more effectively than if a person had not been vaccinated. Please tell me how this can be twisted into a beneficial vaccination/immune response.
"both free and antibody-bound spike, which was detectable only in patients who developed vaccine-induced myocarditis" +
"There is growing in vitro evidence that spike itself can stimulate cardiac pericytes dysfunc-tion23 or inflame the endothelium" +
"the spike antigen itself, which evades antibody recognition rather than invoking immune hyperactivation, may contribute to myocarditis in these individuals" =
"these results do not alter the risk-benefit ratio favoring vaccination against COVID-19 to prevent severe clinical outcomes"
The linked publication shows spike protein in exosomes was still circulating 4 months after the last injection with the Pfizer mRNA vaccine, in all 6 people they checked, at relatively low but variable levels. And besides giving young people myocarditis if they hit the spike-protein jackpot, what else are those spike-covered exosomes doing while floating around in the blood?
Interesting. If there was no evidence of autoimmunity this strongly suggests that the cause of the myocarditis is free spike in circulation. I had previously assumed that it was the circulation of LNPs which resulted in spikes being manufactured in cells in the heart lining - but that would presumably result in an autoimmune response. Or are BOTH mechanisms in play?
Could the difference be due to intramuscular versus intravenous vaccination? I’ve read that the shots weren’t necessarily done in such a way that the vaccine remained in the muscle. Just a thought…
“The vaccines will definitely kill your child, but at least they didn’t die of Covid”.
Thanks guys.
Re: “Although the implications of this finding must be better understood, these results do not alter the risk-benefit ratio favoring vaccination against COVID-19 to prevent severe clinical outcomes.”
Who is actually at risk of “severe clinical outcomes” with COVID-19?
I can't get too excited about finessed explanations of the molecular mechanism of spike's cardiotoxicity. The shots and their presumptuous mRNA platform are the problem and should be banned as any sort of 'public health' tool. Whether the siited study might lead to a treatment for the 'vaccine' injured might be another story.
Every day of delay is moar munny!
How these “scientists” can live with themselves is beyond me.
Soooo....myocarditis is OK ? No issues here to see ??
The sigh....implications of all this are so profound and overwhelming.
I'snt this proof of ADE?
How can worsening of clinical outcome after vaccination ever be considered good? There was increased spike uptake leading to myocarditis. Anotherwords antibodies did not neutralize it. Spike ended up in the cell undisturbed. Isnt that what happens in ADE, spike enters the cell more effectively than if a person had not been vaccinated. Please tell me how this can be twisted into a beneficial vaccination/immune response.
Thank you for bringing that one to the surface.
Hum - they got myocarditis - SMH -more money for the criminal
Cartel as long as the person “needs” treatment & meds & hospitalization, etc (remind anyone of the lab rats spinning the wheel)?
The jab is unfit for man or beast.
Could it have to do with if the vaccine reaches a blood vessel when it’s injected?
Whatever the reason, this was all rolled out too quickly. Accidents or not serious problems were doomed to happen.
1 + 1 + 1 = 4:
"both free and antibody-bound spike, which was detectable only in patients who developed vaccine-induced myocarditis" +
"There is growing in vitro evidence that spike itself can stimulate cardiac pericytes dysfunc-tion23 or inflame the endothelium" +
"the spike antigen itself, which evades antibody recognition rather than invoking immune hyperactivation, may contribute to myocarditis in these individuals" =
"these results do not alter the risk-benefit ratio favoring vaccination against COVID-19 to prevent severe clinical outcomes"
The linked publication shows spike protein in exosomes was still circulating 4 months after the last injection with the Pfizer mRNA vaccine, in all 6 people they checked, at relatively low but variable levels. And besides giving young people myocarditis if they hit the spike-protein jackpot, what else are those spike-covered exosomes doing while floating around in the blood?
https://journals.aai.org/jimmunol/article/207/10/2405/234284/Cutting-Edge-Circulating-Exosomes-with-COVID-Spike
Interesting. If there was no evidence of autoimmunity this strongly suggests that the cause of the myocarditis is free spike in circulation. I had previously assumed that it was the circulation of LNPs which resulted in spikes being manufactured in cells in the heart lining - but that would presumably result in an autoimmune response. Or are BOTH mechanisms in play?
Could the difference be due to intramuscular versus intravenous vaccination? I’ve read that the shots weren’t necessarily done in such a way that the vaccine remained in the muscle. Just a thought…