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Is it really "lowering the dose" if the self-replication ends up basically making the resulting net amount of e.g., spike protein at the same level?

Many of the side effects that were actually followed in any principled or ethical way (which were not many, because everyone gaslighted people with side effects) were due to the spike protein. So .. what? Maybe the side effects will be slightly delayed at best?

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Fewer LNPs. That would be helpful. But what's the half-life of the antigen and countless other unknowns?

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